Ultrasonication of biphasic mixtures involving water and oil forms water microdroplets, offering a promising platform that spontaneously generates hydrogen peroxide and hydrogen gas. However, the redox mechanisms underpinning these transformations are poorly understood, and most existing studies rely heavily on petroleum-derived alkanes like hexadecane. Herein, we introduce a sustainable alternative by utilizing ethyl palmitate, a renewable and plant-based oil as the organic phase.